Matthew Lee, Ph.D.
Research Assistant Professor
Department:
MD-PHARMACOLOGY / THERAPEUTICS
Business Phone:
(352) 294-5661
Business Email:
youngil.lee@ufl.edu
Teaching Profile
Courses Taught
2022-2025
GMS6476 Fundamentals of Skeletal Muscle
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0003-4993-9038
Publications
Academic Articles
2024
Myospreader improves gene editing in skeletal muscle by myonuclear propagation.
Proceedings of the National Academy of Sciences of the United States of America.
121(19)
[DOI] 10.1073/pnas.2321438121.
[PMID] 38687782.
2024
Potential limitations of micro-dystrophin gene therapy for Duchenne muscular dystrophy.
JCI insight.
9(11)
[DOI] 10.1172/jci.insight.165869.
[PMID] 38713520.
2022
Transcription Factor Hb9 Is Expressed in Glial Cell Lineages in the Developing Mouse Spinal Cord.
eNeuro.
9(6)
[DOI] 10.1523/ENEURO.0214-22.2022.
[PMID] 36265906.
2020
Lifetime analysis of mdx skeletal muscle reveals a progressive pathology that leads to myofiber loss.
Scientific reports.
10(1)
[DOI] 10.1038/s41598-020-74192-9.
[PMID] 33057110.
2019
Sarcopenia: Aging-Related Loss of Muscle Mass and Function.
Physiological reviews.
99(1):427-511
[DOI] 10.1152/physrev.00061.2017.
[PMID] 30427277.
2018
Cycles of myofiber degeneration and regeneration lead to remodeling of the neuromuscular junction in two mammalian models of Duchenne muscular dystrophy.
PloS one.
13(10)
[DOI] 10.1371/journal.pone.0205926.
[PMID] 30379896.
2017
Schwann cells participate in synapse elimination at the developing neuromuscular junction.
Current opinion in neurobiology.
47:176-181
[DOI] 10.1016/j.conb.2017.10.010.
[PMID] 29121585.
2013
Terminal Schwann cells participate in the competition underlying neuromuscular synapse elimination.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
33(45):17724-36
[DOI] 10.1523/JNEUROSCI.3339-13.2013.
[PMID] 24198364.
2011
Changes in aging mouse neuromuscular junctions are explained by degeneration and regeneration of muscle fiber segments at the synapse.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
31(42):14910-9
[DOI] 10.1523/JNEUROSCI.3590-11.2011.
[PMID] 22016524.
2011
Muscles in a mouse model of spinal muscular atrophy show profound defects in neuromuscular development even in the absence of failure in neuromuscular transmission or loss of motor neurons.
Developmental biology.
356(2):432-44
[DOI] 10.1016/j.ydbio.2011.05.667.
[PMID] 21658376.
2009
Rapsyn interacts with the muscle acetylcholine receptor via alpha-helical domains in the alpha, beta, and epsilon subunit intracellular loops.
Neuroscience.
163(1):222-32
[DOI] 10.1016/j.neuroscience.2009.05.057.
[PMID] 19482062.
2008
Identification of a motif in the acetylcholine receptor beta subunit whose phosphorylation regulates rapsyn association and postsynaptic receptor localization.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
28(45):11468-76
[DOI] 10.1523/JNEUROSCI.2508-08.2008.
[PMID] 18987183.
Grants
Aug 2021
ACTIVE
Understanding and Improving Therapies for the Muscular Dystrophies
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Contact Details
Phones:
- Business:
- (352) 294-5661
Emails:
- Business:
- youngil.lee@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100267
GAINESVILLE FL 32610 - Business Street:
-
R5-128
1200 Newell Dr
Gainesville FL 32610