David Hammers, Ph.D.
Assistant Professor
On This Page
Teaching Profile
Courses Taught
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GMS6476 – Fundamentals of Skeletal Muscle
College of Medicine
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PAS5026 – Pharmacotherapeutics I
College of Medicine
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GMS6560 – Molecules to Man: Past, Present and Future Therapeutic Strategies for Disease
College of Medicine
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DEN6262 – Prin of Pharmacology
College of Dentistry
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MDU4002 – Introduction to Medical Science Seminar 2
College of Medicine
Research Profile
The Hammers Lab researches physiological and pathophysiological mechanisms of skeletal and cardiac muscle, particularly those associated with genetic diseases known as muscular dystrophies. The primary motivation of these efforts is to identify potential therapeutic targets that can be exploited to develop treatments for muscle and heart diseases using small molecules and/or adeno-associated virus (AAV)-based gene therapies.
In recent work, the Hammers Lab has identified a group of repurposed drugs that act as “remodeling therapeutics” when used to treat severely diseased muscles by reducing muscle fibrosis and rejuvenating muscle regeneration. These discoveries have led to the initiation of new projects investigating the cellular dynamics that occur during the progression of muscle diseases in the absence and presence of remodeling therapeutics, as well as evaluating the potential for these remodeling therapeutics to improve the long-term efficacy of other current or emerging muscular dystrophy treatment strategies.
Areas of Interest
- Cardiomyopathy
- Fibrosis
- Gene therapy
- Muscular dystrophy
- Regeneration
- Striated Muscle Physiology
- Therapeutic Development
Publications
Academic Articles
Contact Details
- Business:
- (352) 273-9977
- Business:
- dhammers@ufl.edu
- Business Mailing:
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PO Box 100267
GAINESVILLE FL 32610 - Business Street:
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ARB Building R5-234
1200 Newell Drive
GAINESVILLE FL 32610