Niloofar Ghadirian

Niloofar Ghadirian, Ph.D.

Research Assistant Scientist

Department: MD-PHARMACOLOGY / THERAPEUTICS
Business Phone: (480) 859-1513
Business Email: nghadirian@ufl.edu

Publications

Academic Articles
2024
DNA Sequence Control of Enzyme Filamentation and Activation of the SgrAI Endonuclease.
Biochemistry. 63(3):326-338 [DOI] 10.1021/acs.biochem.3c00313. [PMID] 38207281.
2023
Physachenolide C is a Potent, Selective BET Inhibitor.
Journal of medicinal chemistry. 66(1):913-933 [DOI] 10.1021/acs.jmedchem.2c01770. [PMID] 36577036.
2022
High-Resolution Structure of the Nuclease Domain of the Human Parvovirus B19 Main Replication Protein NS1.
Journal of virology. 96(9) [DOI] 10.1128/jvi.02164-21. [PMID] 35435730.
2022
Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity.
The Journal of biological chemistry. 298(4) [DOI] 10.1016/j.jbc.2022.101760. [PMID] 35202658.
2020
Artificial Intelligence for COVID-19 Drug Discovery and Vaccine Development.
Frontiers in artificial intelligence. 3 [DOI] 10.3389/frai.2020.00065. [PMID] 33733182.
2019
The Need for Speed: Run-On Oligomer Filament Formation Provides Maximum Speed with Maximum Sequestration of Activity.
Journal of virology. 93(5) [DOI] 10.1128/JVI.01647-18. [PMID] 30518649.

Contact Details

Phones:
Business:
(480) 859-1513
Emails:
Business:
nghadirian@ufl.edu
Addresses:
Business Street:
1200 NEWELL DR
GAINESVILLE FL 32610