Jessie Barra

Jessie Barra, Ph.D.

Postdoctoral Associate

Department: MD-PHARMACOLOGY / THERAPEUTICS
Business Phone: (352) 294-5349
Business Email: jessiebarra@ufl.edu

Research Profile

Mentor: Holger Russ, PhD

Publications

Academic Articles
2024
Combinatorial genetic engineering strategy for immune protection of stem cell-derived beta cells by chimeric antigen receptor regulatory T cells.
Cell reports. 43(11) [DOI] 10.1016/j.celrep.2024.114994. [PMID] 39561045.
2024
Cryopreservation of Stem Cell-Derived β-Like Cells Enriches for Insulin-Producing Cells With Improved Function.
Diabetes. 73(10):1687-1696 [DOI] 10.2337/db24-0346. [PMID] 39083654.
2024
Peptide Coated Polycaprolactone-Benzalkonium Chloride Nanocapsules for Targeted Drug Delivery to the Pancreatic β-Cell.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2024.07.15.603612. [PMID] 39071322.
2024
Peptide-Coated Polycaprolactone-Benzalkonium Chloride Nanocapsules for Targeted Drug Delivery to the Pancreatic β-Cell.
ACS applied bio materials. 7(10):6451-6466 [DOI] 10.1021/acsabm.4c00621. [PMID] 39315885.
2023
Localized cytotoxic T cell-associated antigen 4 and antioxidant islet encapsulation alters macrophage signaling and induces regulatory and anergic T cells to enhance allograft survival.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 23(4):498-511 [DOI] 10.1016/j.ajt.2023.01.007. [PMID] 36731781.
2023
MDA5-dependent responses contribute to autoimmune diabetes progression and hindrance.
JCI insight. 8(2) [DOI] 10.1172/jci.insight.157929. [PMID] 36512407.
2022
Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes.
Diabetes. 71(12):2793-2803 [DOI] 10.2337/db22-0303. [PMID] 36041196.
2022
Islet transplantation into brown adipose tissue can delay immune rejection.
JCI insight. 7(4) [DOI] 10.1172/jci.insight.152800. [PMID] 35015736.
2022
Stem-Cell-Derived β-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity.
Cells. 11(23) [DOI] 10.3390/cells11233845. [PMID] 36497105.
2021
Xenotransplantation of tannic acid-encapsulated neonatal porcine islets decreases proinflammatory innate immune responses.
Xenotransplantation. 28(6) [DOI] 10.1111/xen.12706. [PMID] 34245064.
2020
Localized Immunosuppression With Tannic Acid Encapsulation Delays Islet Allograft and Autoimmune-Mediated Rejection.
Diabetes. 69(9):1948-1960 [DOI] 10.2337/db20-0248. [PMID] 32586979.
2018
Redox-Dependent Inflammation in Islet Transplantation Rejection.
Frontiers in endocrinology. 9 [DOI] 10.3389/fendo.2018.00175. [PMID] 29740396.
2017
Islet encapsulation with polyphenol coatings decreases pro-inflammatory chemokine synthesis and T cell trafficking.
Biomaterials. 128:19-32 [DOI] 10.1016/j.biomaterials.2017.03.002. [PMID] 28285194.

Grants

Mar 2024 ACTIVE
Orthogonal engineering to suppress autoreactive T cell activation in T1D cell therapy
Role: Principal Investigator
Funding: BREAKTHROUGH T1D – formerly JDRF Intl

Contact Details

Phones:
Business:
(352) 294-5349
Emails:
Addresses:
Business Street:
1200 NEWELL DR
GAINESVILLE FL 32610