Stephen P Baker, Ph.D.
EMERITUS PROF
On This Page
Teaching Profile
Courses Taught
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DEN6262 – Prin of Pharmacology
College of Dentistry
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MDU4002 – Introduction to Medical Science Seminar 2
College of Medicine
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BMS6031 – Foundations of Med
College of Medicine
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GMS7593 – Topics in Pharmacology and Toxicology
College of Medicine
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GMS6590 – Seminar in Pharmacology
College of Medicine
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GMS6009 – Drug Action Principle
College of Medicine
Research Profile
Baker’s research is in the area of cell surface receptors and their coupled signal transduction processes, which involves how cells respond to chemical mediators in their external environment. The model systems under study mainly focus on the beta-adrenergic and adenosine receptors and their subtypes, which mediate a number of important cellular and physiological responses and are targets for drug development. His specific interests include the mechanisms of receptor activation and mechanisms of interaction between receptors (cross-talk), which affect intracellular mediators differently. The design and synthesis of novel receptor ligands are also of interest and include structure-activity relationships for partial agonists, enhanced receptor subtype selectivity, and bifunctional ligands, where a single chemical entity can affect the activity of more than one receptor. Irreversible receptor ligands are also used to study the relationship between receptor occupancy and response (coupling efficiency) and the mechanisms for how this relationship changes during health and disease.
Publications
Academic Articles
Contact Details
- Business:
- (352) 294-5358
- Business:
- spbaker@ufl.edu
- Business Mailing:
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PO Box 100267
GAINESVILLE FL 32610 - Business Street:
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1200 NEWELL DRIVE ARB R5-234
GAINESVILLE FL 32610