David M Baekey,
RES AST SCTST
Department:
Department of Neuroscience
Business Email:
dbaekey@ufl.edu
Teaching Profile
Courses Taught
2011-2018
VEM5111 Animal Systems 2
2017
VEM5115 Veterinary Histology
2011,2013-2015,2015-2017,2017
VME5244 Physiology: Organ Systems
2011-2012,2014-2017
VEM5112 Animal Systems 3
2011-2016
VEM5110 Animal Systems 1
2013
VME6932 Seminar in Physiological Sciences
Publications
Academic Articles
2024
Closed-loop cervical epidural stimulation partially restores ipsilesional diaphragm EMG after acute C2 hemisection.
Respiratory physiology & neurobiology.
320
[DOI] 10.1016/j.resp.2023.104182.
[PMID] 37923238.
2024
Effect of positive allosteric modulation and orthosteric agonism of dopamine D2-like receptors on respiration in mouse models of Rett syndrome.
Respiratory physiology & neurobiology.
328
[DOI] 10.1016/j.resp.2024.104314.
[PMID] 39117159.
2024
Intestinal serotonergic vagal signaling as a mediator of microbiota-induced hypertension.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2024.07.17.603451.
[PMID] 39314425.
2023
Subdiaphragmatic vagal nerve stimulation attenuates the development of hypertension and alters nucleus of the solitary tract transcriptional networks in the spontaneously hypertensive rat.
Physiological genomics.
55(12):606-617
[DOI] 10.1152/physiolgenomics.00016.2023.
[PMID] 37746712.
2022
Fentanyl effects on respiratory neuron activity in the dorsolateral pons.
Journal of neurophysiology.
128(5):1117-1132
[DOI] 10.1152/jn.00113.2022.
[PMID] 36197016.
2021
Heartbeats entrain breathing via baroreceptor-mediated modulation of expiratory activity.
Experimental physiology.
106(5):1181-1195
[DOI] 10.1113/EP089365.
[PMID] 33749038.
2020
Mid-cervical interneuron networks following high cervical spinal cord injury.
Respiratory physiology & neurobiology.
271
[DOI] 10.1016/j.resp.2019.103305.
[PMID] 31553921.
2019
Elevated bone marrow sympathetic drive precedes systemic inflammation in angiotensin II hypertension.
American journal of physiology. Heart and circulatory physiology.
317(2):H279-H289
[DOI] 10.1152/ajpheart.00510.2018.
[PMID] 31150271.
2017
Coupling multielectrode array recordings with silver labeling of recording sites to study cervical spinal network connectivity.
Journal of neurophysiology.
117(3):1014-1029
[DOI] 10.1152/jn.00638.2016.
[PMID] 27974450.
2017
High-frequency epidural stimulation across the respiratory cycle evokes phrenic short-term potentiation after incomplete cervical spinal cord injury.
Journal of neurophysiology.
118(4):2344-2357
[DOI] 10.1152/jn.00913.2016.
[PMID] 28615341.
2017
Intermittent Hypoxia Enhances Functional Connectivity of Midcervical Spinal Interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
37(35):8349-8362
[DOI] 10.1523/JNEUROSCI.0992-17.2017.
[PMID] 28751456.
2017
Intraspinal microstimulation and diaphragm activation after cervical spinal cord injury.
Journal of neurophysiology.
117(2):767-776
[DOI] 10.1152/jn.00721.2016.
[PMID] 27881723.
2016
Power spectral analysis of hypoglossal nerve activity during intermittent hypoxia-induced long-term facilitation in mice.
Journal of neurophysiology.
115(3):1372-80
[DOI] 10.1152/jn.00479.2015.
[PMID] 26683067.
2015
Functional connectivity in raphé-pontomedullary circuits supports active suppression of breathing during hypocapnic apnea.
Journal of neurophysiology.
114(4):2162-86
[DOI] 10.1152/jn.00608.2015.
[PMID] 26203111.
2015
Midcervical neuronal discharge patterns during and following hypoxia.
Journal of neurophysiology.
113(7):2091-101
[DOI] 10.1152/jn.00834.2014.
[PMID] 25552641.
2014
Acute Hypoxia Induces Short Term Potentiation of Mid-Cervical Interneuron Discharge
The FASEB's Journal.
28(1, S)
2014
Altered inflammatory response is associated with an impaired autonomic input to the bone marrow in the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979).
63(3):542-50
[DOI] 10.1161/HYPERTENSIONAHA.113.02722.
[PMID] 24366083.
2014
Cardiorespiratory coupling: common rhythms in cardiac, sympathetic, and respiratory activities.
Progress in brain research.
209:191-205
[DOI] 10.1016/B978-0-444-63274-6.00010-2.
[PMID] 24746049.
2014
Cats That Successfully Vent Gastric Acid-Derived Co2 Exhibit Different Muscle Activation Than Those That Do Not
The FASEB's Journal.
28(1, S)
2014
Functional neural-bone marrow pathways: implications in hypertension and cardiovascular disease.
Hypertension (Dallas, Tex. : 1979).
63(6):e129-39
[DOI] 10.1161/HYPERTENSIONAHA.114.02440.
[PMID] 24688127.
2014
Physiological and pathophysiological interactions between the respiratory central pattern generator and the sympathetic nervous system.
Progress in brain research.
212:1-23
[DOI] 10.1016/B978-0-444-63488-7.00001-X.
[PMID] 25194190.
2013
Apnea Alters the Pattern of Intermittent Hypoxia-Induced Long Term Facilitation in Anesthetized Mice
The FASEB's Journal.
27
2013
Dysfunctional brain-bone marrow communication: a paradigm shift in the pathophysiology of hypertension.
Current hypertension reports.
15(4):377-89
[DOI] 10.1007/s11906-013-0361-4.
[PMID] 23715920.
2013
Retrograde Transynaptic Tracing of the Inspiratory Intercostal Circuitry Following Cervical Spinal Cord Injury in Rats
The FASEB's Journal.
27
2013
Selective Activation of Respiratory Thoracic Efferents in the Spinal Cord of the in Situ Rat Preparation
The FASEB's Journal.
27
2012
Cervical Interneuron Bursting During Hypoxia in Anesthetized Rats
The FASEB's Journal.
26
2012
Discharge Identity of Medullary Inspiratory Neurons is Altered during Repetitive Fictive Cough.
Frontiers in physiology.
3
[DOI] 10.3389/fphys.2012.00223.
[PMID] 22754536.
2012
Gastric Co2 Output Via the Esophagus Increases During Systemic Hypercapnia in Anesthetized Cat
The FASEB's Journal.
26
2010
Analysis and modeling of ensemble recordings from respiratory pre-motor neurons indicate changes in functional network architecture after acute hypoxia.
Frontiers in computational neuroscience.
4
[DOI] 10.3389/fncom.2010.00131.
[PMID] 20890445.
2010
Effect of baroreceptor stimulation on the respiratory pattern: insights into respiratory-sympathetic interactions.
Respiratory physiology & neurobiology.
174(1-2):135-45
[DOI] 10.1016/j.resp.2010.09.006.
[PMID] 20837166.
2010
Respiratory and Mayer wave-related discharge patterns of raphé and pontine neurons change with vagotomy.
Journal of applied physiology (Bethesda, Md. : 1985).
109(1):189-202
[DOI] 10.1152/japplphysiol.01324.2009.
[PMID] 20360432.
2009
Breathing and sleep: measurement methods, genetic influences, and developmental impacts.
ILAR journal.
50(3):248-61
[PMID] 19506312.
2009
Cardio-respiratory coupling depends on the pons.
Respiratory physiology & neurobiology.
168(1-2):76-85
[DOI] 10.1016/j.resp.2009.07.009.
[PMID] 19643216.
2009
Comments on point:counterpoint: respiratory sinus arrhythmia is due to a central mechanism vs. respiratory sinus arrhythmia is due to the baroreflex mechanism.
Journal of applied physiology (Bethesda, Md. : 1985).
106(5):1745-9
[DOI] 10.1152/japplphysiol.00196.2009.
[PMID] 19414628.
2009
Pontine-ventral respiratory column interactions through raphe circuits detected using multi-array spike train recordings.
Journal of neurophysiology.
101(6):2943-60
[DOI] 10.1152/jn.91305.2008.
[PMID] 19297509.
2008
Functional connectivity in the pontomedullary respiratory network.
Journal of neurophysiology.
100(4):1749-69
[DOI] 10.1152/jn.90414.2008.
[PMID] 18632881.
2008
Pontine respiratory-modulated activity before and after vagotomy in decerebrate cats.
The Journal of physiology.
586(17):4265-82
[DOI] 10.1113/jphysiol.2008.152108.
[PMID] 18599543.
2008
Pontomedullary transection attenuates central respiratory modulation of sympathetic discharge, heart rate and the baroreceptor reflex in the in situ rat preparation.
Experimental physiology.
93(7):803-16
[DOI] 10.1113/expphysiol.2007.041400.
[PMID] 18344259.
2005
Arterial pulse modulated activity is expressed in respiratory neural output.
Journal of applied physiology (Bethesda, Md. : 1985).
99(2):691-8
[PMID] 15761086.
2004
Pontine respiratory group neuron discharge is altered during fictive cough in the decerebrate cat.
Respiratory physiology & neurobiology.
142(1):43-54
[PMID] 15351303.
2004
Production of reflex cough by brainstem respiratory networks.
Pulmonary pharmacology & therapeutics.
17(6):369-76
[PMID] 15564078.
2004
Ventrolateral medullary respiratory network participation in the expiration reflex in the cat.
Journal of applied physiology (Bethesda, Md. : 1985).
96(6):2057-72
[PMID] 15133012.
2003
Invited review: Neural network plasticity in respiratory control.
Journal of applied physiology (Bethesda, Md. : 1985).
94(3):1242-52
[PMID] 12571145.
2003
Medullary raphe neuron activity is altered during fictive cough in the decerebrate cat.
Journal of applied physiology (Bethesda, Md. : 1985).
94(1):93-100
[PMID] 12486018.
2001
Medullary respiratory neurones and control of laryngeal motoneurones during fictive eupnoea and cough in the cat.
The Journal of physiology.
534(Pt. 2):565-81
[PMID] 11454973.
2000
Functional connectivity among ventrolateral medullary respiratory neurones and responses during fictive cough in the cat.
The Journal of physiology.
525 Pt 1(Pt 1):207-24
[PMID] 10811738.
2000
Respiratory neural activity during long-term facilitation.
Respiration physiology.
121(2-3):119-33
[PMID] 10963769.
1999
Multimodal medullary neurons and correlational linkages of the respiratory network.
Journal of neurophysiology.
82(1):188-201
[PMID] 10400947.
1999
Responses of simultaneously recorded respiratory-related medullary neurons to stimulation of multiple sensory modalities.
Journal of neurophysiology.
82(1):176-87
[PMID] 10400946.
1998
Ventrolateral medullary respiratory network and a model of cough motor pattern generation.
Journal of applied physiology (Bethesda, Md. : 1985).
84(6):2020-35
[PMID] 9609797.
1997
Cerebellar modulation of cough motor pattern in cats.
Journal of applied physiology (Bethesda, Md. : 1985).
83(2):391-7
[PMID] 9262432.
1996
Brainstem respiratory networks and cough.
Pulmonary pharmacology.
9(5-6):343-7
[PMID] 9232673.
Grants
Dec 2016
– Nov 2021
Modeling the role of the NTS in the neurogenesis of airway defensive behaviors
Role: Co-Investigator
Funding: NATL INST OF HLTH NHLBI
Sep 2016
– Jul 2022
Functional mapping of peripheral and central circuits for airway protection and breathing
Role: Co-Investigator
Funding: NATL INST OF HLTH OD
Oct 2015
– Oct 2020
MISCELLANEOUS DONORS
Role: Principal Investigator
Funding: MISCELLANEOUS DONORS
Sep 2014
– Sep 2017
Plasticity and Activation of Spared Intraspinal Respiratory Circuits Following Spinal Cord Injury
Role: Project Manager
Funding: US DEPT OF DEFENSE
Jul 2013
– May 2019
Angiotensin and neuroimmune activation in hypertension
Role: Project Manager
Funding: NATL INST OF HLTH NHLBI
May 2012
– Apr 2018
Modulation of Phrenic Motoneuron Plasticity after Cervical Spinal Cord Injury
Role: Project Manager
Funding: NATL INST OF HLTH NINDS
Jul 2006
– Dec 2020
21st Century Research & Economic Development Investment Program (REDIP)
Role: Project Manager
Funding: STATE UNIV SYS OF FL BOARD OF GOVERNORS
Contact Details
Emails:
- Business:
- dbaekey@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100244
GAINESVILLE FL 32610 - Business Street:
-
1200 NEWELL DR # R5136
GAINESVILLE FL 32610