Lingbao Ai

Lingbao Ai,

Scientist

Department: MD-HEMATOLOGY/ONCOLOGY
Business Phone: (352) 273-9448
Business Email: lingbao.ai@medicine.ufl.edu

Research Profile

Open Researcher and Contributor ID (ORCID)

0009-0004-8907-8564

Publications

2019
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells.
The Biochemical journal. 476(10):1497-1513 [DOI] 10.1042/BCJ20190177. [PMID] 31072911.
2018
Differential expression and function of CAIX and CAXII in breast cancer: A comparison between tumorgraft models and cells.
PloS one. 13(7) [DOI] 10.1371/journal.pone.0199476. [PMID] 29965974.
2018
UFH-001 cells: A novel triple negative, CAIX-positive, human breast cancer model system.
Cancer biology & therapy. 19(7):598-608 [DOI] 10.1080/15384047.2018.1449612. [PMID] 29561695.
2017
ATM is required for SOD2 expression and homeostasis within the mammary gland.
Breast cancer research and treatment. 166(3):725-741 [DOI] 10.1007/s10549-017-4424-0. [PMID] 28849346.
2016
The Breast Cancer Tumor Suppressor Trim29 Is Expressed Via Atm-Dependent Signaling in Response to Hypoxia
Journal of Biological Chemistry. 291(41):21541-21552 [DOI] 10.1074/jbc.M116.730960. [PMID] 27535224.
2015
Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling.
Breast cancer research and treatment. 151(1):75-87 [DOI] 10.1007/s10549-015-3368-5. [PMID] 25862169.
2014
TRIM29 suppresses TWIST1 and invasive breast cancer behavior.
Cancer research. 74(17):4875-87 [DOI] 10.1158/0008-5472.CAN-13-3579. [PMID] 24950909.
2013
Manganese superoxide dismutase promotes anoikis resistance and tumor metastasis.
Cell death & disease. 4(2) [DOI] 10.1038/cddis.2013.20. [PMID] 23429290.
2012
Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression.
The Journal of biological chemistry. 287(22):18330-41 [DOI] 10.1074/jbc.M112.339317. [PMID] 22493284.
2011
Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation.
Proceedings of the National Academy of Sciences of the United States of America. 108(37):15231-6 [DOI] 10.1073/pnas.1104662108. [PMID] 21896759.
2011
The transglutaminase 2 gene is aberrantly hypermethylated in glioma.
Journal of neuro-oncology. 101(3):429-40 [DOI] 10.1007/s11060-010-0277-7. [PMID] 20596752.
2010
Bisulfite sequencing of DNA.
Current protocols in molecular biology. Chapter 7:Unit 7.9.1-17 [DOI] 10.1002/0471142727.mb0709s91. [PMID] 20583099.
2008
Invasion suppressor cystatin E/M (CST6): high-level cell type-specific expression in normal brain and epigenetic silencing in gliomas.
Laboratory investigation; a journal of technical methods and pathology. 88(9):910-25 [DOI] 10.1038/labinvest.2008.66. [PMID] 18607344.
2008
The transglutaminase 2 gene (TGM2), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer.
Carcinogenesis. 29(3):510-8 [DOI] 10.1093/carcin/bgm280. [PMID] 18174247.
2007
alpha7 Nicotinic receptor gene delivery into mouse hippocampal neurons leads to functional receptor expression, improved spatial memory-related performance, and tau hyperphosphorylation.
Neuroscience. 145(1):314-22 [PMID] 17218065.
2006
Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression.
Cancer research. 66(16):7899-909 [PMID] 16912163.
2006
Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer.
Carcinogenesis. 27(7):1341-8 [PMID] 16501252.

Contact Details

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