Gary Todd, Ph.D
My research focuses on the application of gene therapy strategies to correct functional pathology associated with Duchenne Muscular Dystrophy. My current projects include the application of the baculovirus system to produce and evaluate therapeutic transgenes delivered by both viral and non-viral methods. We are interested in understanding how muscle degeneration associated with the onset and progression of DMD limits the effectiveness of gene therapy strategies. In addition, we are exploring ways to overcome the limitations of size restraint in the design of therapeutic transgenes for viral gene therapy by evaluating methods to deliver large transgenes via non-viral methods to target tissues.