Department Alumni

2017


Name

Degree Date

Thesis/Dissertation Title

Mentor

HUGHES, VERONICA 11/08/2017 Phosphorylation of c-Met: An Underutilized Predictor of Sensitivity to c-Met Inhibition in Preclinical and Clinical Cancer Trials SIEMANN, DIETMAR W
SUDHAN, DHIVYA RAJA 11/14/2017 Evaluation of Aerobic Exercise in Tumor Bearing Mice SIEMANN, DIETMAR W

 

2015


Name

Degree Date

Thesis/Dissertation Title

Mentor

DOMINGUEZ, JAMES, II 12/22/2015 Potential Therapeutic Interventions For Diabetic Microvascular Complications GRANT, MARIA A

 

2014


Name

Degree Date

Thesis/Dissertation Title

Mentor

SUDHAN, DHIVYA RAJA 8/12/2014 Cathepsin L Targeting in Metastatic Disease SIEMANN, DIETMAR W
BIEL, THOMAS G 12/23/2014 Mitofusin 2 Mediates Sirtuin 1 Induced Autophagy to Suppress Liver Ischemia/Reperfusion Injury KIM, JAE SUNG

 

2013


Name

Degree Date

Thesis/Dissertation Title

Mentor

JAHN, STEPHAN C 5/7/2013 Overactive Cdk2 in the Progression and Treatment of Cancer LAW, BRIAN KEITH
BIEL, NIKOLETT MOLNAR 8/13/2013 Angiopoietin-2 Inhibition by the Investigational Ang-2 Antibody Medi3617 in Renal Cell Carcinoma Induced Angiogenesis: Therapeutic Implications SIEMANN, DIETMAR W
PHAM, KIEN TRUNG 8/13/2013 Functions and Therapeutic Targeting of Chemokines and Chemokine Receptors in Glioblastoma Progression HARRISON, JEFFREY K
STREHLER, KEVIN Y E 8/13/2013 Complications of Leptin and Serotonin Agonist Therapy in Regulation of Food Intake and the Promise of Wheel Running Intervention in Rats SCARPACE, PHILIP JAMES

 

2012


Name

Degree Date

Thesis/Dissertation Title

Mentor

WILLIAMS, DUSTIN K 5/8/2012 Activation, Desensitization and Potentiation of Alpha7 Nicotinic Acetylcholine Receptors:  Relevance to Alpha7-Targeted Therapeutics PAPKE, ROGER LEE

 

2011


Name

Degree Date

Thesis/Dissertation Title

Mentor

LIU, CHE 5/3/2011 Functional Significance and Therapeutic Targeting of Chemokines and Chemokine Receptors in Glioblastoma HARRISON, JEFFREY K

 

2010


Name

Degree Date

Thesis/Dissertation Title

Mentor

MIKULSKI, ROSE LYNN 12/21/2010 Kinetics and Structure of Proton Transfer Pathways in Carbonic Anhydrase SILVERMAN, DAVID N

 

2009


Name

Degree Date

Thesis/Dissertation Title

Mentor

FERNANDO, STEPHEN J 5/5/2009 Sleeping Beauty Mediated Targeting of Tumor Endothelial Marker 8 in the Tumor Vasculature of Colorectal Carcinomas in Mice FLETCHER, BRAD S
LAUGHLIN, KATHARINE M 5/5/2009 Function of Hematopoietic- and Neurologic-Expressed Sequence 1 (Hn1) in Cancer HARRISON, JEFFREY K
ZHANG, JIEJIN 5/5/2009 Leptin Antagonist and Soluble Leptin Receptor Block Leptin Action in Vivo: Evidence for an Essential Role of Leptin in Homeostatic Energy Regulation SCARPACE, PHILIP JAMES
DONG, MEIYU 12/22/2009 Targeting Tumor Metastasis-Src Inhibition SIEMANN, DIETMAR W
JUDGE, MELANIE KAE 12/22/2009 The Role of Endocannabinoid Receptor Activity in Young and Aged Rats with High-Fat Feeding SCARPACE, PHILIP JAMES
PARKER, NICOLE NADINE TEOH

 

12/22/2009 Transforming Growth Factor Beta-Induced Tyrosine Phosphorylation of STAT3 and Cellular Invasion is Mediated by IL-6 Secretion in Breast Cancer Cell Lines LAW, BRIAN KEITH

 

2008


Name

Degree Date

Thesis/Dissertation Title

Mentor

CHANG, KYUNG HEE 5/6/2008 Insulin-Like Growth Factor Binding Protein-3 Regulates Hematopoietic Stem Cell and Endothelial Progenitor Cell Function during Vascular Development GRANT, MARIA A

 

2007


Name

Degree Date

Thesis/Dissertation Title

Mentor

BLUM, JASON L. 5/1/2007 Effects of Methoxychlor on the Expression and Activity of Largemouth Bass Estrogen Receptors Alpha, Beta-A and Beta-B In Vivo and In Vitro DENSLOW, NANCY D.
JACKSON, KELLY M. 5/1/2007 A Preclinical Study of Flavopiridol in the Treatment of Acute Lymphoblastic Leukemia HUNGER, STEPHEN P.

 

2006


Name

Degree Date

Thesis/Dissertation Title

Mentor

PAN, HAO 5/6/2006 Targeting Angiogenic Growth Factors in Proliferative Diabetic Retinopathy GRANT, MARIA A
BRAZELLE, WILLIAM D 12/16/2006 Molecular Targeting Strategies Directed at the Tumor Endothelium to Enhance the Efficacy of Cancer Radiotherapy SIEMANN, DIETMAR W
NORRIS, CHRISTINA M 12/16/2006 Impact of Tumor VEGF Expression on the Response to Anti-Cancer Therapies SIEMANN, DIETMAR W
SALMON, BETH ANN 12/16/2006 Characterizing the Tumor Response to Vascular Disrupting Agent Treatment SIEMANN, DIETMAR W

 

2005


Name

Degree Date

Thesis/Dissertation Title

Mentor

PLACZEK, ANDON N. 5/1/2005 Regulation of Alpha7 Nicotinic Acetylcholine Receptor Function and Pharmacology by Amino Acid Sequence in the Second Transmembrane Domain PAPKE, ROGER L.

 

2004


Name

Degree Date

Thesis/Dissertation Title

Mentor

CHEN, SHUZHEN 5/1/2004 TGF-β1 Regulation of Chemokine Receptors in Rat Microglia and Human Macrophages HARRISON, JEFFREY K.
TAYLOR, DAVID G. 8/1/2004 Roles of Sarcoplasmic Reticular Ca2+ -Atpase 2a and Action Potential Duration in Rat Normal and Hypertrophied Myocardium KNOT, HARM
HANDAYANI, RENITA 12/1/2004 Prospective Cancer Chemoprevention Agents: Mechanisms of the Effects of a Soy Isoflavone Concentrate and Vitamin E Succinate on the Regulation of P21 (CIP1/WAF1) Gene Expression SHIVERICK, KATHLEEN T.

 

2003


Name

Degree Date

Thesis/Dissertation Title

Mentor

GARDON, MONICA L. 8/1/2003 Functional Remodeling of the Renal and Cerebral Resistance Vasculature in Hypertensive Rats KNOT, HARM
LI, GANG 8/1/2003 Effects of the Melanocortin Agonist Melanotan II, Central Propopiomelanocortin and Interleukin-6 Gene Therapies on the Regulation of Body Weight and Homeostasis SCARPACE, PHILIP J.
WILSEY, JARED T. 8/1/2003 Potent Anorexic and Lipopeni Effects of Central Leptin Gene Therapy are Blocked by Diet-Induced Obesity: Evidence for Impaired Leptin Receptor Expression/Signal Transduction in Obesity and Reversal by Caloric Restriction SCARPACE, PHILIP J.
CAO, XUEFANG 12/1/2003 Cleavage of Bax to P18 Bax Facilitates Stress-Induced Apoptosis MAY, W. STATFORD

 

2001


Name

Degree Date

Thesis/Dissertation Title

Mentor

BOWMAN, CHRISTOPHER J. 5/1/2001 Gene Regulation in Teleosts by Estradiol and Estrogen Mimics DENSLOW, NANCY D.
HEARN, AMY S. 8/1/2001 Product Inhibition in Human Manganese Superoxide Dismutase SILVERMAN, DAVID N.
McGARRY, MICHELLE A. 8/1/2001 Benzo(a)pyrene-Mediated Effects on Cellular Adhesion and Signal Transduction Pathways in Endometrial Cancer SHIVERICK, KATHLEEN T.
SAMEDI, VON G. 8/1/2001 Antiproliferative Effects of Isoflavonoids on Prostate Cancer Cells and Antitumorigenic Effects in Xenograft Nude Mice SHIVERICK, KATHLEEN T.

 

2000


Name

Degree Date

Thesis/Dissertation Title

Mentor

WARRINGTON, KENNETH H, JR, 5/1/2000 Gene Therapy Approaches for Solid Tumors: Ovarian Carcinoma and Bioreductive Chemotherapy SIEMANN, DIETMAR W.
LI, LINGYUN 12/1/2000 Studies of the Anticancer Effects of the Vascular Targeting Agent Combretastatin A-4 Disodium Phosphate (CA4DP) SIEMANN, DIETMAR W.

 

1999


Name

Degree Date

Thesis/Dissertation Title

Mentor

KARKANIAS, NIKOLAS B. 8/1/1999 Lithium Modulates Desensitization of AMPA Receptors PAPKE, ROGER L.
OZECK, MARK J. 12/1/1999 A1 Adenosine Receptor Activation Increases Leptin Production by Rat White Adipose Tissue BELARDINELLI, LUIZ
WATTERSON, JEANNETTE M. 12/1/1999 In Vitro Studies on a Putative Molecular Mechanism of Action of Valproic Acid in Treatment of Bipolar Disorder MEYER, EDWIN M.

 

1998


Name

Degree Date

Thesis/Dissertation Title

Mentor

KLOPP, ALAN J. 5/1/1998 Characterization of DNA Cleavage Fragment Populations Induced by Topoisomerase II Active Drugs ROWE, THOMAS C.
RUDOLPH, JOSEPH G. 5/1/1998 Effects of Chronic Ethanol on NMDA Receptor Pharmacology and Physiology: Possible Mechanisms for the Development of Ethanol Tolerance and Dependence CREWS, FULTON T.
KUMAR, MONICA V. 8/1/1998 Vitamin A and β3-Adrenergic Regulation of Leptin and UCP1 Gene Expression: Role in Energy Homeostasis and Senescence SCARPACE, PHILIP J.
FRANCIS, MICHAEL M. 12/1/1998 Subunit-Specific Determinants of Function and Pharmacology of Nicotinic Acetylcholine Receptors PAPKE, ROGER L.
JIANG, YAN 12/1/1998 Expression of Chemokine Receptors in Rat Central Nervous System HARRISON, JEFFREY K.
NOWICKI, STEPHEN T. 12/1/1998 Characterization of the Mechanism of the Sub-Type Selective, Slow-Dissociation of a Carbostyril Based β-Adrenergic Receptor Agonist From the β2-Adrenergic Receptor RICHARDS, NIGEL G. J.

 

1997


Name

Degree Date

Thesis/Dissertation Title

Mentor

SRINIVAS, MIDUTURU 8/1/1997 The Importance of A1-Adenosine Receptor Reserve in the Heart BELARDINELLI, LUIZ
WANG, SAMUEL 8/1/1997 Characterization of Novel AAV-Derived Gene Transfer Approaches for Mitotic and Differentiated Cells MEYER, EDWIN M.
GRANTLEY, CHARLES D. 12/1/1997 Xenobiotic Effects on Gene Expression in Endometrial Cells and Placental Tissue SHIVERICK, KATHLEEN T.

 

1996


Name

Degree Date

Thesis/Dissertation Title

Mentor

JENNINGS, AMY A. 5/1/1996 Identification and Characterization of Two Novel Rat CXC Chemokine Receptors ROWE, THOMAS C.
DUNSTAN, CHERYL-ANN N. 8/1/1996 Identification and Characterization of Two Novel Rat CXC Chemokine Receptors SHIVERICK, KATHLEEN T.
ZHANG, LIYAN 12/1/1996 Xenobiotic-Dependent Regulation of Gene Expression in Human Placental Cell Lines FREGLY, MELVIN J.

 

1995


Name

Degree Date

Thesis/Dissertation Title

Mentor

ANDALORO, VINCENT J. 2/1/1995 Neurotrophic Ramifications of Muscarinic Receptor Stimulation of Intracellular Calcium Signals in SH-SY5Y Cells CREWS, FULTON T.
WANG, DESUO 5/1/1995 Ionic Basis of the Negative Dromotropic and Inotropic Actions of Adenosine BELARDINELLI, LUIZ
AMOAH-APRAKU, BISMARK 8/1/1995 Regulation of Inducible Nitric Oxide Synthase in Murine Proximal Tubule Epithelial Cells GUZMAN, NICOLAS J.
DUKES, KAREN R. 12/1/1995 Selective Inheritance of Mitochondrial DNA in Heteroplasmic Mice NEIMS, ALLEN H.
MASTEN, SCOTT A. 12/1/1995 Evaluation of Potential Mechanisms for Xenobiotic-Mediated Disruption of Lymphocyte Function and Responsiveness SHIVERICK, KATHLEEN T.

 

1994


Name

Degree Date

Thesis/Dissertation Title

Mentor

ZHANG, JIAHUI 12/1/1994 Characterization and Use of A1 Adenosie Receptor Irreversible Ligands BAKER, STEPHEN P.

 

1993


Name

Degree Date

Thesis/Dissertation Title

Mentor

PATEL, RAJIV A. 8/1/1993 The Regulatory Role of Lipids in Transforming Virus Infectivity and in Growth Factor Mediated Cellular Mitogenesis and Differentiation CREWS, FULTON T.

 

1992


Name

Degree Date

Thesis/Dissertation Title

Mentor

LoGRASSO, PHILIP V. 5/1/1992 Source of the Catalytic Differencecs Between Human Carbonic Anhydrases III and II as Determined by Site-Specific Mutagenesis SILVERMAN, DAVID N.
LAWRENCE, JEFFREY W. 8/1/1992 DNA Topoisomerase Inhibitors Induce a Loss of Mitochondrial DNA in Mammalian Cells ROWE, THOMAS C.
FLEMING, LYNNE M. 12/1/1992 Opiod Receptor-Mediated Inhibition of Protein Phosphorylation in Rat Brain CHILDERS, STEVEN R.
KONKOY, CHRISTOPHER S. 12/1/1992 Pharmacological Properties of Kappa Opioid Receptors in Guinea Pig Brain CHILDERS, STEVEN R.
PACHECO, MARY A. 12/1/1992 Characterization of Endogenous Aminoalkylindole/Cannabinoid Systems in Brain CHILDERS, STEVEN R.
WOZNIAK-RYDZEWSKI, MAGDALENA 12/1/1992 Differential Regulation of Alpha-1A and Alpha-1B Adrenergic Receptor Subtypes in Neuronal and Astroglial Cell Cultures BAKER, STEPHEN P.
XIE, FAN 12/1/1992 Interaction of Adenosine Receptors in a Smooth Muscle Cell Line BAKER, STEPHEN P.

 

1991


Name

Degree Date

Thesis/Dissertation Title

Mentor

CLARKE, DAYNA J. 5/1/1991 Alpha Andrenoceptors in Rabbit Renal Inner Medullary Collecting Duct Cells GARG, LAL C.
SJAK-SHIE, NELIDA N. 5/1/1991 The Effects of Potential Trophic or Cytoprotective Agents in Cholinergically Hypofunctional Rat Brains MEYER, EDWIN M.
DANSO, DANIEL Y. 8/1/1991 Differentiation and De-Differentiation in FRLA-209-15 Cells and the Potential Role of Polyamines SHIVERICK, KATHLEEN T.
FOLGER, WALTER H. 8/1/1991 Characterization of the Role of Thromboxane in the Aorta and Kidney and the Thromboxane Receptor in the Glomerulus WILCOX, CHRISTOPHER S.
BORGERT, CHRISTOPHER J. 12/1/1991 Phosphorylation of Type I and Type II DNA Topoisomerases in a Human Tumor Cell in Line ROWE, THOMAS C.

 

1990


Name

Degree Date

Thesis/Dissertation Title

Mentor

KRAJNIAK, KEVIN 8/1/1990 In Search of Extramolluscan FMRFamide-Related Peptides GREENBERG, MICHAEL J.
OLSON, JOHN A., JR. 12/1/1990 Developmental Regulation of Constitutive and Angiotensin II-Induced Protein Secretion by Astrocytes of the Brain SHIVERICK, KATHLEEN T.

 

1989


Name

Degree Date

Thesis/Dissertation Title

Mentor

PAPANEK, PAULA E. 5/1/1989 Cold-Induced Hypertension in Rats FREGLY, MELVIN J.
BOLDEN, CAROLYN P. 12/1/1989 Characterization of Acetylethylcholine Mustard and Basal Turnover of the Muscarinic Cholinergic Receptor in GH3 Cells BAKER, STEPHEN P.
KROLL, DAVID J. 12/1/1989 Regulation of DNA Topoisomerase II in a Human Tumor Cell Line ROWE, THOMAS C.

 

1988


Name

Degree Date

Thesis/Dissertation Title

Mentor

PAYZA, KEMAL 4/1/1988 FMRF Receptors of Helix Aspersa GREENBERG, MICHAEL J.
SCOTT, JAMES A. 4/1/1988 Central Biogenic Amine Receptor Adaptation During Antidepressant Treatment: Studies Directed at Therapeutic Mechanisms CREWS, FULTON T.
McARDLE, SHARI 8/1/1988 Pharmacological Characterization of the Phosphoinositide Second Messenger System in the Rabbit System GARG, LAL C.
STANDIFER, KELLY M. 8/1/1988 Characterization of Some Carbostyril Congeners Having Novel Beta-Adrenoreceptor Agonist Properties BAKER, STEPHEN P.
RICHARDS-SUMNERS, ELAINE M. 12/1/1988 Catecholamine and Angiotensin II Interactions in Primary Cultures of Brain Cells PHILLIPS, M. I.

 

1987


Name

Degree Date

Thesis/Dissertation Title

Mentor

McCLUSKY, RICHARD A. 8/1/1987 Synthesis and Properties of Submicron Albumin Spheres GOLDBERG, E. P.
BORTELL, RITA B. 12/1/1987 Effects of Polyamine Analogs on Mitochondrial DNA and Cell Growth NEIMS, ALLEN H.
RAULLI, ROBERT E. 12/1/1987 Alpha-Adrenergic Stimulation of Phosphoinositide Hydrolysis in the Rat Brain CREWS, FULTON T.

 

1986


Name

Degree Date

Thesis/Dissertation Title

Mentor

LAMBERT, SCOTT M. 8/1/1986 Proteolytic Degradation of the Neuropeptide FMRFamide by Molluscan Myocardial Membranes GREENBURG, MICHAEL J.

 

1985


Name

Degree Date

Thesis/Dissertation Title

Mentor

BOTTIGLIERI, DENISE F. 12/1/1985 Lipid Modulation of Neuronal Cholinergic Activity MEYER, EDWIN M.

 

1984


Name

Degree Date

Thesis/Dissertation Title

Mentor

HEIMAN, ANN S. 8/1/1984 Studies on Agents Which Modify Mast Cell Stimulation-Secretion Coupling CREWS, FULTON T.
KARARLI, TUGRUL T. 12/1/1984 Kinetics and Inhibition of Carbonic Anhydrase III: Comparison with Carbonic Anhydrase II SILVERMAN, DAVID N.
NELSON, CAROL A. 12/1/1984 Studies on Agents Which Modify Mast Cell Stimulation-Secretion Coupling BAKER, STEPHEN P.

 

1983


Name

Degree Date

Thesis/Dissertation Title

Mentor

FELDSTEIN, JUDITH B. 8/1/1983 Purification and Characterization of Carbonic Anhydrase from the Saliva and Red Cells of the Rat SILVERMAN, DAVID N.

 

1982


Name

Degree Date

Thesis/Dissertation Title

Mentor

DOYLE, JAMES W. 12/1/1982 Membrane Actions of a Protein Cytotoxin Isolated from a Carribean Sea Anemone, Stoichactis helianthus KEM, WILLIAM R.

 

1980


Name

Degree Date

Thesis/Dissertation Title

Mentor

KIRNER, DEBORAH L. 12/1/1980 Studies on Cyanide Release from Acrylonitrile in Rate Hepatic Microsomes LEIBMAN, KENNETH C.

 

1979


Name

Degree Date

Thesis/Dissertation Title

Mentor

CHU, CHUN-JUNG 3/1/1979 Chemotherapy of an Experimental Glioma with Autonomic Drugs CHAPMAN, SHARON K.
TOWN, CHRISTOPHER 12/1/1978 The In Vitro Dechlorination of Some Polychlorinated Ethanes LEIBMAN, KENNETH C.

 

1978


Name

Degree Date

Thesis/Dissertation Title

Mentor

MATTHEWS, ROBERT T. 6/1/1978 Studies on Diethylcholine: Its Mechanism of Action and Usefulness as an Antiparkinsonism Agent CHIOU, C. Y.
TRZECIAKOWSKI, JEROME 8/1/1978 Parasympathomimetric and Ocular Hypotensive Properties of N-Demethylated Carbachol CHIOU, C. Y.

 

1977


Name

Degree Date

Thesis/Dissertation Title

Mentor

FRETTHOLD, DAVID W. 5/1/1977 The Effect of Alterations of the Components of the Bicarbonate Buffer System on Skeletal Muscle Contraction, Potassium Content and Resting Potential GARG, LAL C.

 

1976


Name

Degree Date

Thesis/Dissertation Title

Mentor

ZIMMERMAN, THOM J. 6/1/1976 The Effects of Acetazolamide Upon the Formation of Aqueous Humor in Dog and Monkey VOGH, BETTY P.
HAYWOOD, JOSEPH R. 12/1/1976 Autonomic Influences on the Production of Cerebrospinal Fluid VOGH, BETTY P.
LIDDELL, NORMAN E. 12/1/1976 Pharmacological Studies on the Use of Carbonic Anhydrase Inhibitors in Salicylate Intoxication MAREN, THOMAS H.

 

1975


Name

Degree Date

Thesis/Dissertation Title

Mentor

KEARIN, MICHAEL M. 6/1/1975 Studies of the Inflammatory Constituent of the Fire Sponge, Tedania ignis KEM, WILLIAM R.
ROWELL, PETER P. 8/1/1975 Pharmacological Studies of In Vivo Inhabitors of Choline Acetyltransferase CHIOU, C. Y.
ACKERMAN, DENNIS M. 12/1/1975 The Effect of Experimental Diabetes on Drug Metabolism LEIBMAN, KENNETH C.
DUNLAP, CLAUD E., III 12/1/1975 Role of Divalent Metal Ion in the Interaction Between Chromomycin A3 and Deoxyribonucleic Acid SILVERMAN, DAVID N.

 

1973


Name

Degree Date

Thesis/Dissertation Title

Mentor

MALAGODI, MARJORIE H. 12/1/1973 Pharmacological Studies of 8-(N,N-Diethylamino) Octly 3,4,5-Trimethoxybenzoate Hydrochloride (TMB-8) CHIOU, C. Y.

 

1972


Name

Degree Date

Thesis/Dissertation Title

Mentor

DVORCHIK, BARRY H. 6/1/1972 The Distribution, Binding, Fate, and Toxicity of p,p’-DDT [2,2-bis(p-chlorophenl)-1,1,1-trichloroethane] in the Dogfish, Squalus acanthias MAREN, THOMAS H.
SILVESTRI, RAUL 12/1/1972 Role of Plasma in the Inactivation of Paraoxon in Different Species of Laboratory and Domestic Animals and In Man LEIBMAN, KENNETH C.
WECKER, LYNN 12/1/1972 The Effects of 3,3-Dimethyl-1-Butanol Carbamate on Cholinergic Neurotransmission CHIOU, C. Y.

 

1971


Name

Degree Date

Thesis/Dissertation Title

Mentor

WHYATT, PHILIP L. 12/1/1971 Barbiturate Inhibition of Growth and of the Synthesis of DNA, RNA and Protein in Cultured Mammalian Cells CRAMER, JOHN W.

 

1970


Name

Degree Date

Thesis/Dissertation Title

Mentor

NAEGER, LEONARD L. 8/1/1970 Mechanisms of Decaborane Toxictiy LEIBMAN, KENNETH C.

 

1969


Name

Degree Date

Thesis/Dissertation Title

Mentor

GARG, LAL C. 5/22/1969 Effects of Drugs on Ion Transport and Aqueous Humor Formation OPPELT, W. WALTER