Department Alumni

2017

Name	Degree Date	Thesis/Dissertation Title	Mentor
HUGHES, VERONICA	11/08/2017	Phosphorylation of c-Met: An Underutilized Predictor of Sensitivity to c-Met Inhibition in Preclinical and Clinical Cancer Trials	SIEMANN, DIETMAR W
SUDHAN, DHIVYA RAJA	11/14/2017	Evaluation of Aerobic Exercise in Tumor Bearing Mice	SIEMANN, DIETMAR W

2015

Name	Degree Date	Thesis/Dissertation Title	Mentor
DOMINGUEZ, JAMES, II	12/22/2015	Potential Therapeutic Interventions For Diabetic Microvascular Complications	GRANT, MARIA A

2014

Name	Degree Date	Thesis/Dissertation Title	Mentor
SUDHAN, DHIVYA RAJA	8/12/2014	Cathepsin L Targeting in Metastatic Disease	SIEMANN, DIETMAR W
BIEL, THOMAS G	12/23/2014	Mitofusin 2 Mediates Sirtuin 1 Induced Autophagy to Suppress Liver Ischemia/Reperfusion Injury	KIM, JAE SUNG

2013

Name	Degree Date	Thesis/Dissertation Title	Mentor
JAHN, STEPHAN C	5/7/2013	Overactive Cdk2 in the Progression and Treatment of Cancer	LAW, BRIAN KEITH
BIEL, NIKOLETT MOLNAR	8/13/2013	Angiopoietin-2 Inhibition by the Investigational Ang-2 Antibody Medi3617 in Renal Cell Carcinoma Induced Angiogenesis: Therapeutic Implications	SIEMANN, DIETMAR W
PHAM, KIEN TRUNG	8/13/2013	Functions and Therapeutic Targeting of Chemokines and Chemokine Receptors in Glioblastoma Progression	HARRISON, JEFFREY K
STREHLER, KEVIN Y E	8/13/2013	Complications of Leptin and Serotonin Agonist Therapy in Regulation of Food Intake and the Promise of Wheel Running Intervention in Rats	SCARPACE, PHILIP JAMES

2012

Name	Degree Date	Thesis/Dissertation Title	Mentor
WILLIAMS, DUSTIN K	5/8/2012	Activation, Desensitization and Potentiation of Alpha7 Nicotinic Acetylcholine Receptors: Relevance to Alpha7-Targeted Therapeutics	PAPKE, ROGER LEE

2011

Name	Degree Date	Thesis/Dissertation Title	Mentor
LIU, CHE	5/3/2011	Functional Significance and Therapeutic Targeting of Chemokines and Chemokine Receptors in Glioblastoma	HARRISON, JEFFREY K

2010

Name	Degree Date	Thesis/Dissertation Title	Mentor
MIKULSKI, ROSE LYNN	12/21/2010	Kinetics and Structure of Proton Transfer Pathways in Carbonic Anhydrase	SILVERMAN, DAVID N

2009

Name	Degree Date	Thesis/Dissertation Title	Mentor
FERNANDO, STEPHEN J	5/5/2009	Sleeping Beauty Mediated Targeting of Tumor Endothelial Marker 8 in the Tumor Vasculature of Colorectal Carcinomas in Mice	FLETCHER, BRAD S
LAUGHLIN, KATHARINE M	5/5/2009	Function of Hematopoietic- and Neurologic-Expressed Sequence 1 (Hn1) in Cancer	HARRISON, JEFFREY K
ZHANG, JIEJIN	5/5/2009	Leptin Antagonist and Soluble Leptin Receptor Block Leptin Action in Vivo: Evidence for an Essential Role of Leptin in Homeostatic Energy Regulation	SCARPACE, PHILIP JAMES
DONG, MEIYU	12/22/2009	Targeting Tumor Metastasis-Src Inhibition	SIEMANN, DIETMAR W
JUDGE, MELANIE KAE	12/22/2009	The Role of Endocannabinoid Receptor Activity in Young and Aged Rats with High-Fat Feeding	SCARPACE, PHILIP JAMES
PARKER, NICOLE NADINE TEOH	12/22/2009	Transforming Growth Factor Beta-Induced Tyrosine Phosphorylation of STAT3 and Cellular Invasion is Mediated by IL-6 Secretion in Breast Cancer Cell Lines	LAW, BRIAN KEITH

2008

Name	Degree Date	Thesis/Dissertation Title	Mentor
CHANG, KYUNG HEE	5/6/2008	Insulin-Like Growth Factor Binding Protein-3 Regulates Hematopoietic Stem Cell and Endothelial Progenitor Cell Function during Vascular Development	GRANT, MARIA A

2007

Name	Degree Date	Thesis/Dissertation Title	Mentor
BLUM, JASON L.	5/1/2007	Effects of Methoxychlor on the Expression and Activity of Largemouth Bass Estrogen Receptors Alpha, Beta-A and Beta-B In Vivo and In Vitro	DENSLOW, NANCY D.
JACKSON, KELLY M.	5/1/2007	A Preclinical Study of Flavopiridol in the Treatment of Acute Lymphoblastic Leukemia	HUNGER, STEPHEN P.

2006

Name	Degree Date	Thesis/Dissertation Title	Mentor
PAN, HAO	5/6/2006	Targeting Angiogenic Growth Factors in Proliferative Diabetic Retinopathy	GRANT, MARIA A
BRAZELLE, WILLIAM D	12/16/2006	Molecular Targeting Strategies Directed at the Tumor Endothelium to Enhance the Efficacy of Cancer Radiotherapy	SIEMANN, DIETMAR W
NORRIS, CHRISTINA M	12/16/2006	Impact of Tumor VEGF Expression on the Response to Anti-Cancer Therapies	SIEMANN, DIETMAR W
SALMON, BETH ANN	12/16/2006	Characterizing the Tumor Response to Vascular Disrupting Agent Treatment	SIEMANN, DIETMAR W

2005

Name	Degree Date	Thesis/Dissertation Title	Mentor
PLACZEK, ANDON N.	5/1/2005	Regulation of Alpha7 Nicotinic Acetylcholine Receptor Function and Pharmacology by Amino Acid Sequence in the Second Transmembrane Domain	PAPKE, ROGER L.

2004

Name	Degree Date	Thesis/Dissertation Title	Mentor
CHEN, SHUZHEN	5/1/2004	TGF-β1 Regulation of Chemokine Receptors in Rat Microglia and Human Macrophages	HARRISON, JEFFREY K.
TAYLOR, DAVID G.	8/1/2004	Roles of Sarcoplasmic Reticular Ca2+ -Atpase 2a and Action Potential Duration in Rat Normal and Hypertrophied Myocardium	KNOT, HARM
HANDAYANI, RENITA	12/1/2004	Prospective Cancer Chemoprevention Agents: Mechanisms of the Effects of a Soy Isoflavone Concentrate and Vitamin E Succinate on the Regulation of P21 (CIP1/WAF1) Gene Expression	SHIVERICK, KATHLEEN T.

2003

Name	Degree Date	Thesis/Dissertation Title	Mentor
GARDON, MONICA L.	8/1/2003	Functional Remodeling of the Renal and Cerebral Resistance Vasculature in Hypertensive Rats	KNOT, HARM
LI, GANG	8/1/2003	Effects of the Melanocortin Agonist Melanotan II, Central Propopiomelanocortin and Interleukin-6 Gene Therapies on the Regulation of Body Weight and Homeostasis	SCARPACE, PHILIP J.
WILSEY, JARED T.	8/1/2003	Potent Anorexic and Lipopeni Effects of Central Leptin Gene Therapy are Blocked by Diet-Induced Obesity: Evidence for Impaired Leptin Receptor Expression/Signal Transduction in Obesity and Reversal by Caloric Restriction	SCARPACE, PHILIP J.
CAO, XUEFANG	12/1/2003	Cleavage of Bax to P18 Bax Facilitates Stress-Induced Apoptosis	MAY, W. STATFORD

2001

Name	Degree Date	Thesis/Dissertation Title	Mentor
BOWMAN, CHRISTOPHER J.	5/1/2001	Gene Regulation in Teleosts by Estradiol and Estrogen Mimics	DENSLOW, NANCY D.
HEARN, AMY S.	8/1/2001	Product Inhibition in Human Manganese Superoxide Dismutase	SILVERMAN, DAVID N.
McGARRY, MICHELLE A.	8/1/2001	Benzo(a)pyrene-Mediated Effects on Cellular Adhesion and Signal Transduction Pathways in Endometrial Cancer	SHIVERICK, KATHLEEN T.
SAMEDI, VON G.	8/1/2001	Antiproliferative Effects of Isoflavonoids on Prostate Cancer Cells and Antitumorigenic Effects in Xenograft Nude Mice	SHIVERICK, KATHLEEN T.

2000

Name	Degree Date	Thesis/Dissertation Title	Mentor
WARRINGTON, KENNETH H, JR,	5/1/2000	Gene Therapy Approaches for Solid Tumors: Ovarian Carcinoma and Bioreductive Chemotherapy	SIEMANN, DIETMAR W.
LI, LINGYUN	12/1/2000	Studies of the Anticancer Effects of the Vascular Targeting Agent Combretastatin A-4 Disodium Phosphate (CA4DP)	SIEMANN, DIETMAR W.

1999

Name	Degree Date	Thesis/Dissertation Title	Mentor
KARKANIAS, NIKOLAS B.	8/1/1999	Lithium Modulates Desensitization of AMPA Receptors	PAPKE, ROGER L.
OZECK, MARK J.	12/1/1999	A1 Adenosine Receptor Activation Increases Leptin Production by Rat White Adipose Tissue	BELARDINELLI, LUIZ
WATTERSON, JEANNETTE M.	12/1/1999	In Vitro Studies on a Putative Molecular Mechanism of Action of Valproic Acid in Treatment of Bipolar Disorder	MEYER, EDWIN M.

1998

Name	Degree Date	Thesis/Dissertation Title	Mentor
KLOPP, ALAN J.	5/1/1998	Characterization of DNA Cleavage Fragment Populations Induced by Topoisomerase II Active Drugs	ROWE, THOMAS C.
RUDOLPH, JOSEPH G.	5/1/1998	Effects of Chronic Ethanol on NMDA Receptor Pharmacology and Physiology: Possible Mechanisms for the Development of Ethanol Tolerance and Dependence	CREWS, FULTON T.
KUMAR, MONICA V.	8/1/1998	Vitamin A and β3-Adrenergic Regulation of Leptin and UCP1 Gene Expression: Role in Energy Homeostasis and Senescence	SCARPACE, PHILIP J.
FRANCIS, MICHAEL M.	12/1/1998	Subunit-Specific Determinants of Function and Pharmacology of Nicotinic Acetylcholine Receptors	PAPKE, ROGER L.
JIANG, YAN	12/1/1998	Expression of Chemokine Receptors in Rat Central Nervous System	HARRISON, JEFFREY K.
NOWICKI, STEPHEN T.	12/1/1998	Characterization of the Mechanism of the Sub-Type Selective, Slow-Dissociation of a Carbostyril Based β-Adrenergic Receptor Agonist From the β2-Adrenergic Receptor	RICHARDS, NIGEL G. J.

1997

Name	Degree Date	Thesis/Dissertation Title	Mentor
SRINIVAS, MIDUTURU	8/1/1997	The Importance of A1-Adenosine Receptor Reserve in the Heart	BELARDINELLI, LUIZ
WANG, SAMUEL	8/1/1997	Characterization of Novel AAV-Derived Gene Transfer Approaches for Mitotic and Differentiated Cells	MEYER, EDWIN M.
GRANTLEY, CHARLES D.	12/1/1997	Xenobiotic Effects on Gene Expression in Endometrial Cells and Placental Tissue	SHIVERICK, KATHLEEN T.

1996

Name	Degree Date	Thesis/Dissertation Title	Mentor
JENNINGS, AMY A.	5/1/1996	Identification and Characterization of Two Novel Rat CXC Chemokine Receptors	ROWE, THOMAS C.
DUNSTAN, CHERYL-ANN N.	8/1/1996	Identification and Characterization of Two Novel Rat CXC Chemokine Receptors	SHIVERICK, KATHLEEN T.
ZHANG, LIYAN	12/1/1996	Xenobiotic-Dependent Regulation of Gene Expression in Human Placental Cell Lines	FREGLY, MELVIN J.

1995

Name	Degree Date	Thesis/Dissertation Title	Mentor
ANDALORO, VINCENT J.	2/1/1995	Neurotrophic Ramifications of Muscarinic Receptor Stimulation of Intracellular Calcium Signals in SH-SY5Y Cells	CREWS, FULTON T.
WANG, DESUO	5/1/1995	Ionic Basis of the Negative Dromotropic and Inotropic Actions of Adenosine	BELARDINELLI, LUIZ
AMOAH-APRAKU, BISMARK	8/1/1995	Regulation of Inducible Nitric Oxide Synthase in Murine Proximal Tubule Epithelial Cells	GUZMAN, NICOLAS J.
DUKES, KAREN R.	12/1/1995	Selective Inheritance of Mitochondrial DNA in Heteroplasmic Mice	NEIMS, ALLEN H.
MASTEN, SCOTT A.	12/1/1995	Evaluation of Potential Mechanisms for Xenobiotic-Mediated Disruption of Lymphocyte Function and Responsiveness	SHIVERICK, KATHLEEN T.

1994

Name	Degree Date	Thesis/Dissertation Title	Mentor
ZHANG, JIAHUI	12/1/1994	Characterization and Use of A1 Adenosie Receptor Irreversible Ligands	BAKER, STEPHEN P.

1993

Name	Degree Date	Thesis/Dissertation Title	Mentor
PATEL, RAJIV A.	8/1/1993	The Regulatory Role of Lipids in Transforming Virus Infectivity and in Growth Factor Mediated Cellular Mitogenesis and Differentiation	CREWS, FULTON T.

1992

Name	Degree Date	Thesis/Dissertation Title	Mentor
LoGRASSO, PHILIP V.	5/1/1992	Source of the Catalytic Differencecs Between Human Carbonic Anhydrases III and II as Determined by Site-Specific Mutagenesis	SILVERMAN, DAVID N.
LAWRENCE, JEFFREY W.	8/1/1992	DNA Topoisomerase Inhibitors Induce a Loss of Mitochondrial DNA in Mammalian Cells	ROWE, THOMAS C.
FLEMING, LYNNE M.	12/1/1992	Opiod Receptor-Mediated Inhibition of Protein Phosphorylation in Rat Brain	CHILDERS, STEVEN R.
KONKOY, CHRISTOPHER S.	12/1/1992	Pharmacological Properties of Kappa Opioid Receptors in Guinea Pig Brain	CHILDERS, STEVEN R.
PACHECO, MARY A.	12/1/1992	Characterization of Endogenous Aminoalkylindole/Cannabinoid Systems in Brain	CHILDERS, STEVEN R.
WOZNIAK-RYDZEWSKI, MAGDALENA	12/1/1992	Differential Regulation of Alpha-1A and Alpha-1B Adrenergic Receptor Subtypes in Neuronal and Astroglial Cell Cultures	BAKER, STEPHEN P.
XIE, FAN	12/1/1992	Interaction of Adenosine Receptors in a Smooth Muscle Cell Line	BAKER, STEPHEN P.

1991

Name	Degree Date	Thesis/Dissertation Title	Mentor
CLARKE, DAYNA J.	5/1/1991	Alpha Andrenoceptors in Rabbit Renal Inner Medullary Collecting Duct Cells	GARG, LAL C.
SJAK-SHIE, NELIDA N.	5/1/1991	The Effects of Potential Trophic or Cytoprotective Agents in Cholinergically Hypofunctional Rat Brains	MEYER, EDWIN M.
DANSO, DANIEL Y.	8/1/1991	Differentiation and De-Differentiation in FRLA-209-15 Cells and the Potential Role of Polyamines	SHIVERICK, KATHLEEN T.
FOLGER, WALTER H.	8/1/1991	Characterization of the Role of Thromboxane in the Aorta and Kidney and the Thromboxane Receptor in the Glomerulus	WILCOX, CHRISTOPHER S.
BORGERT, CHRISTOPHER J.	12/1/1991	Phosphorylation of Type I and Type II DNA Topoisomerases in a Human Tumor Cell in Line	ROWE, THOMAS C.

1990

Name	Degree Date	Thesis/Dissertation Title	Mentor
KRAJNIAK, KEVIN	8/1/1990	In Search of Extramolluscan FMRFamide-Related Peptides	GREENBERG, MICHAEL J.
OLSON, JOHN A., JR.	12/1/1990	Developmental Regulation of Constitutive and Angiotensin II-Induced Protein Secretion by Astrocytes of the Brain	SHIVERICK, KATHLEEN T.

1989

Name	Degree Date	Thesis/Dissertation Title	Mentor
PAPANEK, PAULA E.	5/1/1989	Cold-Induced Hypertension in Rats	FREGLY, MELVIN J.
BOLDEN, CAROLYN P.	12/1/1989	Characterization of Acetylethylcholine Mustard and Basal Turnover of the Muscarinic Cholinergic Receptor in GH3 Cells	BAKER, STEPHEN P.
KROLL, DAVID J.	12/1/1989	Regulation of DNA Topoisomerase II in a Human Tumor Cell Line	ROWE, THOMAS C.

1988

Name	Degree Date	Thesis/Dissertation Title	Mentor
PAYZA, KEMAL	4/1/1988	FMRF Receptors of Helix Aspersa	GREENBERG, MICHAEL J.
SCOTT, JAMES A.	4/1/1988	Central Biogenic Amine Receptor Adaptation During Antidepressant Treatment: Studies Directed at Therapeutic Mechanisms	CREWS, FULTON T.
McARDLE, SHARI	8/1/1988	Pharmacological Characterization of the Phosphoinositide Second Messenger System in the Rabbit System	GARG, LAL C.
STANDIFER, KELLY M.	8/1/1988	Characterization of Some Carbostyril Congeners Having Novel Beta-Adrenoreceptor Agonist Properties	BAKER, STEPHEN P.
RICHARDS-SUMNERS, ELAINE M.	12/1/1988	Catecholamine and Angiotensin II Interactions in Primary Cultures of Brain Cells	PHILLIPS, M. I.

1987

Name	Degree Date	Thesis/Dissertation Title	Mentor
McCLUSKY, RICHARD A.	8/1/1987	Synthesis and Properties of Submicron Albumin Spheres	GOLDBERG, E. P.
BORTELL, RITA B.	12/1/1987	Effects of Polyamine Analogs on Mitochondrial DNA and Cell Growth	NEIMS, ALLEN H.
RAULLI, ROBERT E.	12/1/1987	Alpha-Adrenergic Stimulation of Phosphoinositide Hydrolysis in the Rat Brain	CREWS, FULTON T.

1986

Name	Degree Date	Thesis/Dissertation Title	Mentor
LAMBERT, SCOTT M.	8/1/1986	Proteolytic Degradation of the Neuropeptide FMRFamide by Molluscan Myocardial Membranes	GREENBURG, MICHAEL J.

1985

Name	Degree Date	Thesis/Dissertation Title	Mentor
BOTTIGLIERI, DENISE F.	12/1/1985	Lipid Modulation of Neuronal Cholinergic Activity	MEYER, EDWIN M.

1984

Name	Degree Date	Thesis/Dissertation Title	Mentor
HEIMAN, ANN S.	8/1/1984	Studies on Agents Which Modify Mast Cell Stimulation-Secretion Coupling	CREWS, FULTON T.
KARARLI, TUGRUL T.	12/1/1984	Kinetics and Inhibition of Carbonic Anhydrase III: Comparison with Carbonic Anhydrase II	SILVERMAN, DAVID N.
NELSON, CAROL A.	12/1/1984	Studies on Agents Which Modify Mast Cell Stimulation-Secretion Coupling	BAKER, STEPHEN P.

1983

Name	Degree Date	Thesis/Dissertation Title	Mentor
FELDSTEIN, JUDITH B.	8/1/1983	Purification and Characterization of Carbonic Anhydrase from the Saliva and Red Cells of the Rat	SILVERMAN, DAVID N.

1982

Name	Degree Date	Thesis/Dissertation Title	Mentor
DOYLE, JAMES W.	12/1/1982	Membrane Actions of a Protein Cytotoxin Isolated from a Carribean Sea Anemone, Stoichactis helianthus	KEM, WILLIAM R.

1980

Name	Degree Date	Thesis/Dissertation Title	Mentor
KIRNER, DEBORAH L.	12/1/1980	Studies on Cyanide Release from Acrylonitrile in Rate Hepatic Microsomes	LEIBMAN, KENNETH C.

1979

Name	Degree Date	Thesis/Dissertation Title	Mentor
CHU, CHUN-JUNG	3/1/1979	Chemotherapy of an Experimental Glioma with Autonomic Drugs	CHAPMAN, SHARON K.
TOWN, CHRISTOPHER	12/1/1978	The In Vitro Dechlorination of Some Polychlorinated Ethanes	LEIBMAN, KENNETH C.

1978

Name	Degree Date	Thesis/Dissertation Title	Mentor
MATTHEWS, ROBERT T.	6/1/1978	Studies on Diethylcholine: Its Mechanism of Action and Usefulness as an Antiparkinsonism Agent	CHIOU, C. Y.
TRZECIAKOWSKI, JEROME	8/1/1978	Parasympathomimetric and Ocular Hypotensive Properties of N-Demethylated Carbachol	CHIOU, C. Y.

1977

Name	Degree Date	Thesis/Dissertation Title	Mentor
FRETTHOLD, DAVID W.	5/1/1977	The Effect of Alterations of the Components of the Bicarbonate Buffer System on Skeletal Muscle Contraction, Potassium Content and Resting Potential	GARG, LAL C.

1976

Name	Degree Date	Thesis/Dissertation Title	Mentor
ZIMMERMAN, THOM J.	6/1/1976	The Effects of Acetazolamide Upon the Formation of Aqueous Humor in Dog and Monkey	VOGH, BETTY P.
HAYWOOD, JOSEPH R.	12/1/1976	Autonomic Influences on the Production of Cerebrospinal Fluid	VOGH, BETTY P.
LIDDELL, NORMAN E.	12/1/1976	Pharmacological Studies on the Use of Carbonic Anhydrase Inhibitors in Salicylate Intoxication	MAREN, THOMAS H.

1975

Name	Degree Date	Thesis/Dissertation Title	Mentor
KEARIN, MICHAEL M.	6/1/1975	Studies of the Inflammatory Constituent of the Fire Sponge, Tedania ignis	KEM, WILLIAM R.
ROWELL, PETER P.	8/1/1975	Pharmacological Studies of In Vivo Inhabitors of Choline Acetyltransferase	CHIOU, C. Y.
ACKERMAN, DENNIS M.	12/1/1975	The Effect of Experimental Diabetes on Drug Metabolism	LEIBMAN, KENNETH C.
DUNLAP, CLAUD E., III	12/1/1975	Role of Divalent Metal Ion in the Interaction Between Chromomycin A3 and Deoxyribonucleic Acid	SILVERMAN, DAVID N.

1973

Name	Degree Date	Thesis/Dissertation Title	Mentor
MALAGODI, MARJORIE H.	12/1/1973	Pharmacological Studies of 8-(N,N-Diethylamino) Octly 3,4,5-Trimethoxybenzoate Hydrochloride (TMB-8)	CHIOU, C. Y.

1972

Name	Degree Date	Thesis/Dissertation Title	Mentor
DVORCHIK, BARRY H.	6/1/1972	The Distribution, Binding, Fate, and Toxicity of p,p’-DDT [2,2-bis(p-chlorophenl)-1,1,1-trichloroethane] in the Dogfish, Squalus acanthias	MAREN, THOMAS H.
SILVESTRI, RAUL	12/1/1972	Role of Plasma in the Inactivation of Paraoxon in Different Species of Laboratory and Domestic Animals and In Man	LEIBMAN, KENNETH C.
WECKER, LYNN	12/1/1972	The Effects of 3,3-Dimethyl-1-Butanol Carbamate on Cholinergic Neurotransmission	CHIOU, C. Y.

1971

Name	Degree Date	Thesis/Dissertation Title	Mentor
WHYATT, PHILIP L.	12/1/1971	Barbiturate Inhibition of Growth and of the Synthesis of DNA, RNA and Protein in Cultured Mammalian Cells	CRAMER, JOHN W.

1970

Name	Degree Date	Thesis/Dissertation Title	Mentor
NAEGER, LEONARD L.	8/1/1970	Mechanisms of Decaborane Toxictiy	LEIBMAN, KENNETH C.

1969

Name	Degree Date	Thesis/Dissertation Title	Mentor
GARG, LAL C.	5/22/1969	Effects of Drugs on Ion Transport and Aqueous Humor Formation	OPPELT, W. WALTER