Publication Alert: Papke Lab

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Congratulations to the Papke lab on their recent publication: “Silent agonists for α7 nicotinic acetylcholine receptors” The publication discuss models for the activation and desensitization of α7 nicotinic acetylcholine receptors (nAChRs) and the effects of efficacious type II positive allosteric modulators (PAMs) that destabilize α7 desensitized states.