Publication from the Kopinke Lab

The first paper produced in the Kopinke Lab has been accepted by the journal, Cell!

Graduate student Alessandra Norris and Daniel Kopinke, the PI, discovered that pre-adipocytes possess a primary cilium, which acts as a cellular antenna to sense and interpret environmental cues. Genetically removing cilia from preadipocytes prevented their differentiation into mature fat cells. As a consequence, white adipose tissue expansion was dramatically repressed. This finding points to cilia as a gatekeeper of healthy fat and, hopefully, will lead to novel therapies for obesity, diabetes and heart disease.  

Congratulations! We’re so proud!

Cell journal cover


Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis