A paper authored by four UF Pharmacology and Therapeutics faculty members was published in the newest issue of The Journal of Neuroscience.
The paper, “Primary Cilia on Horizontal Basal Cells Regulate Regeneration of the Olfactory Epithelium,” was co-authored by Department Chair Jeffrey Martens, Ph.D., as well as faculty members Warren Green, Ph.D., and Jeremy McIntyre, Ph.D alongside Ariell Joiner, Ph.D., from the University of Michigan and James Schwob, Ph.D. of Tufts University.
The paper describes research from the Martens lab that shows for the first time that stem cells in the olfactory epithelium possess primary cilia and that these cilia are necessary for regeneration of the olfactory epithelium after injury.
These findings suggest that the mechanisms of penetrance for ciliopathies in the olfactory system may include alterations in olfactory epithelium maintenance and regeneration.
The full paper can be read on The Journal of Neuroscience website.